Researchers have developed a genetic tool in mice to speed the discovery of novel genes involved in cancer. The system -- called PiggyBac -- involves disrupting or altering the mouse genome using ...

Researchers have developed a genetic tool in mice to speed the discovery of novel genes involved in cancer. The system – called PiggyBac – has already been used by the team to identify novel candidate ...

Current reprogramming strategies commonly utilize viral infection or plasmid transfection for the delivery of reprogramming factor transgenes. Although these methods are useful, they have several ...

Researchers in the U.S. and in China are using new genetic approaches to speed up cancer research and develop gene therapy. They are using transposons, or jumping genes, which were discovered 50 years ...

A jumping gene first identified in a cabbage-eating moth may one day provide a safer, target-specific alternative to viruses for gene therapy, researchers say. They compared the ability of the four ...

A transposon-based approach has been added to the growing arsenal of technologies to produce transgene-free and potentially safer induced pluripotent stem cells. The ability to generate induced ...

While much has been said about the rise of biologic-based therapeutics, less has been said about the challenges that stand in the way of producing them reliably and economically. In the initial phase ...

Transposons are often likened to genetic parasites – rarely benefit the organisms in whose genomes they appear – they have been a boon to scientists. Geneticists have been using these "jumping genes" ...

A jumping gene first identified in a cabbage-eating moth may one day provide a safer, target-specific alternative to viruses for gene therapy, researchers say. They compared the ability of the four ...