The extracellular matrix (ECM) initiates mechanical cues that activate intracellular signaling through matrix–cell interactions. In blood vessels, additional mechanical cues derived from the pulsatile ...
Effect of MiR-338-3p on epithelial-mesenchymal transition in gastric cancer cells by targeting ZEB2 and MACC1 and regulation of MACC1/c-Met signaling. This is an ASCO Meeting Abstract from the 2014 ...
This is a preview. Log in through your library . Abstract Increased affinity of integrins for the extracellular matrix (activation) regulates cell adhesion and migration, extracellular matrix assembly ...
Phase II study of the angiogenesis inhibitor AZD2171 in first line, progressive, unresectable, advanced metastatic renal cell carcinoma (RCC): A trial of the PMH Phase II Consortium No significant ...
Extracellular vesicles are tiny spheres that cells release to send molecules or messages to other cells, often as a means of seeding cancer elsewhere in the body. In a new study, researchers found ...
Within tissues, cells are embedded in complex, three-dimensional structures known as the extracellular matrix. Their biomechanical interactions play a crucial role in numerous biological processes.
Left: the two peptide chains of an integrin receptor, colored red and blue, extend through the cell membrane into the extracellular space. Center: when bound to the common form of the FN10 ligand or ...
Cancer cells produce small amounts of their own form of type 1 collagen (Col1), creating a unique extracellular matrix that affects the tumor microbiome and protects against immune responses, ...
A fluorescent probe for visualizing the signaling dynamics in metastatic cancer cells has been developed. A research team at the University of Turku (Finland), led by Johanna Ivaska and James Conway, ...
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